Active Ingredient	Synthetic opioid analgesic
Manufacturer	Global Medicine
Packaging	100 and 500 Tablets in 1 Box
Strength	50 Mg 100 Mg 200 Mg
Delivery Time	7 To 10 Days
SKU:	TRAMADOL

Tramadol

What is Tramadol?

• Tramadol is a synthetic opioid analgesic (painkiller).

• Developed in Germany in the 1970s and approved for use in the U.S. in the 1990s.

• It is often considered a “weaker” opioid compared to morphine or oxycodone, but it still carries addiction and overdose risks.

• Sold under brand names like Ultram, ConZip, Ryzolt.

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Medical Uses (Benefits)

Doctors prescribe tramadol for:

• Moderate to moderately severe pain (post-surgery, injury, chronic conditions).

• Chronic pain management, such as osteoarthritis, fibromyalgia, and neuropathic pain.

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How It Works

• Dual mechanism of action:

  1. Opioid effect: Binds to mu-opioid receptors in the brain to block pain signals.

  2. Non-opioid effect: Increases levels of serotonin and norepinephrine (neurotransmitters), helping to further reduce pain perception.

This makes it different from many other opioids.

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Benefits (When Used Correctly)

• Effective for chronic pain when other non-opioid medicines are not enough.

• Considered to have a lower risk of respiratory depression compared to stronger opioids.

• Provides pain relief without needing very high doses.

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Harms & Risks

• Addiction and Dependence – though weaker than other opioids, long-term use can still cause addiction.

• Side effects: nausea, vomiting, dizziness, constipation, headache, drowsiness, sweating.

• Seizure Risk – especially in high doses or in people with epilepsy.

• Serotonin Syndrome – dangerous condition if taken with antidepressants (SSRIs, SNRIs, MAOIs).

• Overdose danger – slowed breathing, unconsciousness, even death when misused or mixed with alcohol/other sedatives.

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Abuse Concerns

• Tramadol is sometimes abused because it can cause euphoria (feeling high).

• Considered less potent than other opioids, but still controlled in many countries (U.S. – Schedule IV).

• Overuse has contributed to the global opioid misuse problem, though to a smaller degree compared to Oxycodone or Hydrocodone.

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Conclusion

• Tramadol is a useful pain medication for moderate pain and chronic conditions.

• Its dual mechanism makes it different from many opioids.

• However, it is not risk-free — it can still cause addiction, dependence, and dangerous side effects if

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